Impact and challenges of infection control in a public sector intensive care unit: Experience from a low resourced country

  • Muhammad Shoaib Khan Department of Pathology and Microbiology, Aga Khan University
  • Saeeda Haider Department of Anaesthesia, Dow University of Health Sciences, Karachi
  • Safia Zafar Siddiqui Department of Anaesthesia, Dow University of Health Sciences, Karachi
  • Afia Zafar Department of Pathology and Microbiology, Aga Khan University, Karachi
  • Faisal Riaz Malik Department of Pathology and Microbiology, Aga Khan University, Karachi
  • Rumina Hasan Department of Pathology and Microbiology, Aga Khan University, Karachi

Abstract

Impact of introducing infection control (IC) on VAP rates in a low resource public sector intensive care unit was investigated. The study was conducted in two parts; pre and post intervention periods. 285 patients admitted during the pre intervention period (July to December 2007) and 426 patients admitted during post intervention period (September 2008 to May 2009) were included. IC was implemented through educational sessions, introduction of a computerized surveillance program for recording data, and the establishment of a team responsible for monitoring and improving IC. VAP rate following the interventions was noted to be 3.5% (15/426), a significant decrease (p<0.0001) from the pre intervention rate of 13% (37/285). Case fatality reduced from 57% (21/37) to 53% (8/15) post intervention. 81% VAP causing organisms were multidrug resistant (resistant to ≥2 classes of antibiotics) in the post intervention period compared to 91% in the pre intervention period. We conclude that although stringent interventional measures were effective in reducing VAP rates, in our experience impact on antimicrobial resistance and on mortality was limited. Regular surveillance and team work were essential components that were required. Significant challenges faced included the need of continuous education to modify behaviors and improve attitudes towards IC.

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Author Biographies

Muhammad Shoaib Khan, Department of Pathology and Microbiology, Aga Khan University
Research Assistant
Saeeda Haider, Department of Anaesthesia, Dow University of Health Sciences, Karachi
Professor
Safia Zafar Siddiqui, Department of Anaesthesia, Dow University of Health Sciences, Karachi
Assistant Professor
Afia Zafar, Department of Pathology and Microbiology, Aga Khan University, Karachi
Professor
Faisal Riaz Malik, Department of Pathology and Microbiology, Aga Khan University, Karachi
Data Manager
Rumina Hasan, Department of Pathology and Microbiology, Aga Khan University, Karachi
Professor
Published
2010-11-19
How to Cite
Khan, M., Haider, S., Siddiqui, S., Zafar, A., Malik, F., & Hasan, R. (2010). Impact and challenges of infection control in a public sector intensive care unit: Experience from a low resourced country. International Journal of Infection Control, 7(3). https://doi.org/10.3396/ijic.v7i3.6333
Section
Original Articles