Barriers and enablers to the implementation of infection prevention and control guidance in a Ugandan healthcare facility – a theory-informed qualitative study to guide intervention design

Authors

  • Andrew Owen Kalule Safeguarding Health through Infection Prevention Research Group, Research Centre for Health, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, UK https://orcid.org/0000-0001-9356-1218
  • Kay Currie Safeguarding Health through Infection Prevention Research Group, Research Centre for Health, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, UK
  • Lesley Price, Prof Safeguarding Health through Infection Prevention Research Group, Research Centre for Health, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, UK https://orcid.org/0000-0001-5678-4818

DOI:

https://doi.org/10.3396/ijic.v21.23768

Keywords:

infection prevention and control guidance, behaviour change, qualitative, low-resource settings

Abstract

Implementing Infection Prevention and Control (IPC) guidance is crucial for reducing healthcare-associated infection (HAI) rates. However, achieving behavioural and organisational change is necessary for successful implementation. To understand these changes, it is important to identify the barriers and facilitators to IPC implementation, supported by theoretical analysis.

This paper presents the second stage of a study conducted in Uganda, aiming to analyse barriers and enablers to IPC guideline implementation and provide preliminary recommendations for intervention design. Interviews with frontline healthcare workers were conducted, and qualitative content analysis helped identify specific barriers and enablers. The Theoretical Domains Framework (TDF) was used to categorise and map these factors to the BCW/COM-B model, enabling the identification of intervention functions supporting IPC implementation.

The findings highlighted various important factors influencing IPC implementation, including social influences, environmental context and resources, knowledge, skills, professional role and identity, behavioural regulation, memory, attention and decision processes, goals, beliefs about capabilities, beliefs about consequences, intentions, emotion, and reinforcement. All components of the COM-B model (Capability, Opportunity, Motivation) were deemed significant in IPC implementation. Key intervention functions such as enablement, environmental restructuring, training and education, persuasion, and incentivization were identified as potentially useful for designing interventions to improve IPC implementation.

In conclusion, the analysis emphasized the interconnectedness and importance of capability, opportunity, and motivation in adopting IPC guidance in such contexts. The study offers recommendations for future interventions, including education and training programs, leveraging memory and attention, addressing beliefs about consequences, and improving social influences and support systems. These insights can guide the development of effective strategies to enhance IPC implementation.

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Author Biographies

Andrew Owen Kalule, Safeguarding Health through Infection Prevention Research Group, Research Centre for Health, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, UK

Andrew is an expert in Infection Prevention and Control, and a skilled Development Professional, with a focus on IPC guidance development, implementation and evaluation of public health programs. He has over 7 years of versatile experience across Bangladesh, Uganda, and the United Kingdom. Andrew has recently accomplished a PhD in Infection Control, concentrating on the application of IPC guidance in low-income nations. He plays a significant role as a Healthcare Scientist at NHS National Services Scotland, actively shaping IPC guidance, and also takes on the role of a part-time lecturer at the University of East London.

Kay Currie, Safeguarding Health through Infection Prevention Research Group, Research Centre for Health, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, UK

Kay Currie is a Professor of Nursing & Applied Healthcare Research in the Department of Nursing & Community Health at Glasgow Caledonian University, where she is involved in social science-based infection prevention and control research.  Kay has a special interest in improving healthcare quality, specifically person-centred care through effective professional practice.  Her current research and teaching focus are on understanding and responding to patient experience, staff behaviours, and organisational contexts in the areas of healthcare-associated infection and antimicrobial resistance.

Recent work includes research related to staff and patient views on the acceptability of suspended visiting during norovirus outbreaks (TSV Noro Project); barriers and enablers to staff compliance with MRSA screening (AMR-BESH Project); public, patient and staff views on the acceptability of screening for CPE; patient experience of healthcare-associated infection; behavioural insights into pet owner and veterinarian actions and attitudes related to antibiotic use in companion animals; barriers and enablers to antimicrobial stewardship in acute care hospitals (The BEAMS Project).

 

Lesley Price, Prof, Safeguarding Health through Infection Prevention Research Group, Research Centre for Health, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, UK

Lesley is the co-lead of the Safeguarding Health through Infection Prevention and Control Research Group at Glasgow Caledonian University. She leads a programme of work on infection prevention and control interventions.

Lesley has a special interest in improving the evidence base for standard and transmission-based infection prevention and control interventions with a particular focus on hand hygiene research. Whilst specialising in quantitative research methods and systematic reviews, she often leads work packages within mixed methods research projects.

Recent completed hand hygiene work includes a pragmatic randomised controlled trial of the 6-step vs 3-step hand hygiene technique and research evaluating the sustained effect of participation in a Guinness World Record for the largest hand hygiene relay and the effect of wearing fake tan on hand hygiene.

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Published

2025-06-24

How to Cite

Kalule, A. O., Currie, K., & Price, L. (2025). Barriers and enablers to the implementation of infection prevention and control guidance in a Ugandan healthcare facility – a theory-informed qualitative study to guide intervention design. International Journal of Infection Control, 21. https://doi.org/10.3396/ijic.v21.23768

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Section

Original Articles

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